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- W2377052951 abstract "Objective To investigate the clinical significance of E-cadherin expression for the prognosis of breast cancer and triple-negative breast cancer (TNBC). Methods We randomly enrolled 280 cases of invasive breast cancer in our hospital from 2003 to 2005 (the patients with invasive lobular carcinomas were exempted). E-cadherin expression was determined by immunohistochemistry. Log Rank survival curve was used to analyze the correlation between E-cadherin expression and the prognosis of breast cancer and TNBC. Results In all the 280 cases, the prognosis of E-cadherin-negative patients was significantly worse than that of E-cadherin-positive patients (overall survival: Log Rank=19.99,P=0.00; disease-free survival: Log Rank=21.42, P=0.00). In the 32 TNBC cases, the prognosis of E-cadherin-negative patients was significantly worse than that of E-cadherin-positive patients (overall survival: Log Rank=4.67, P=0.03; disease-free survival: Log Rank=6.54, P=0.01). Conclusion E-cadherin is a prognostic factor for breast cancer and TNBC, which might be useful to further classify the subgroups of TNBC." @default.
- W2377052951 created "2016-06-24" @default.
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- W2377052951 date "2013-01-01" @default.
- W2377052951 modified "2023-09-28" @default.
- W2377052951 title "Correlation between E-cadherin expression and the prognosis of breast cancer and triple-negative breast cancer" @default.
- W2377052951 hasPublicationYear "2013" @default.
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