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- W2377165917 abstract "Objective:To explore the efficacy and safety of dezocine combined with dexmedetomidine in sedation of postoperative patients with tracheal tubes after orthognathic surgery.Methods:Sixty postoperative patients undergoing orthognathic surgery were enrolled and randomized into dexmedetomidine group(control group) and dezocine combined with dexmedetomidine group(combination group) with 30 cases in each group.The heart rate(HR),mean arterial pressure(MAP).respiratory rate(RR),pulse oxygen saturation(SpO_2) and the dose of dexmedetomidine in different periods were compared between the two groups.Results:HR at 12 h and 24 h in the combination group were significantly higher than those in the control group(P0.05).MAP at 6 h and 12 h in the combination group were significantly higher than those in the control group(P0.05).The amounts of dexmedetomidine in the combination group during 0.5-1 h and 1-6 h time periods were lower than those in the control group(P0.05).The adverse reaction rate showed no significant difference between the two groups(P0.05).Conclusions:Dezocine combined with dexmedetomidine is safe and effective for sedation in postoperative patients undergoing orthognathic surgery,which can reduce the dose of dexmedetomidine and rate of adverse reaction." @default.
- W2377165917 created "2016-06-24" @default.
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- W2377165917 date "2013-01-01" @default.
- W2377165917 modified "2023-09-26" @default.
- W2377165917 title "Efficacy and Safety of Dezocine Combined with Dexmedetomidine in Sedation after Orthognathic Surgery" @default.
- W2377165917 hasPublicationYear "2013" @default.
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