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- W2377172027 abstract "Objective To analyze the resistance of Acinetobacter to β-lactamases and investigate the main resistance mechanisms of Acinetobacter. Methods The confirmatory test,double-disc diffusion test, isoelectric focus and PCR amplification were carried out to detect the β-lactamases produced by 126 Acinetobacter. Results Out of the 126 strains of Acinetobacter 38 strains produced AmpC β-lactamases as determined by three-dimensional extract test and ampC gene amplification. All of the strains didn’t produce ESBLS. ampR gene was identified in 25 strains and ampD gene was observed in 11 strains. Conclusion AmpC and TEM-1 β-lactamases are the major β-lactamases. The ampD and ampR gene influence the activity of AmpC β-lactamases. The resistant rate of cephalosporin of the third generation is over 50%. The resistance rate to imipenem is the lowest." @default.
- W2377172027 created "2016-06-24" @default.
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- W2377172027 date "2006-01-01" @default.
- W2377172027 modified "2023-09-23" @default.
- W2377172027 title "Analysis of resistant spectrums and mechanism of Acinetobacter to β-lactams" @default.
- W2377172027 hasPublicationYear "2006" @default.
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