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- W2377199596 abstract "Objective To study the relationship between plasma urotensin Ⅱ level and macroangiopathy in patients with type 2 diabetes mellitus(DM).Methods One hundred and three patients with type 2 DM and 31 healthy controls were selected.According to the results of artery cartery ultrasonography,the patients with type 2 diabetes mellitus were divided into three groups,normal group(DM-Ⅰ group,n=39),intima-media thickness over 0.9 mm group(DM-Ⅱ group,n=27) and atheromatous plaque group(DM-Ⅲ group,n=37).Fasting plasma urotensin Ⅱ level was measured by radioimmunoassay.Results Mean plasma urotensin Ⅱ level in DM group was significantly higher than that in control group(0.55±0.22) pg/L vs(0.32±0.11) pg/L(P=0.010);Mean plasma urotensin Ⅱ level in DM-Ⅱ group and in DM-Ⅲ group were significantly higher than that in DM-Ⅰ group(0.68±0.29) pg/L and(0.59±0.24) pg/L vs(0.49±0.18) pg/L(all P0.001).Mean plasma urotensin Ⅱ level in DM-Ⅲ group was significantly lower than that in DM-Ⅱ group(P=0.01).Conclusion A possible role for urotensin Ⅱexists in some metabolic process and macroangiopathy progression of type 2 DM,especially acts in the formation of atheromatous plaque.Plasma urotensin Ⅱ level seems to be a useful factor to indicate macroangiopathy in patients with type 2 DM." @default.
- W2377199596 created "2016-06-24" @default.
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- W2377199596 date "2008-01-01" @default.
- W2377199596 modified "2023-09-24" @default.
- W2377199596 title "Relationship between plasma urotensin II level and macroangiopathy in patients with type 2 diabetes mellitus" @default.
- W2377199596 hasPublicationYear "2008" @default.
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