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- W2377202347 abstract "Objective:To investigate the correlation of MRI findings of vasogenic brain edema (VBE) after ischemia reperfusion of rats and its VEGF expression of brain tissue.Methods:The thread occlusion of right middle cerebral artery (MCA) was made to set up VBE models in rats.Dynamic evaluation with MRI was performed to evaluate VBE.The specimen were analyzed at various time immunohistochemisically after reperfusion.Results:The signs of VBE were most prominent at 1～2d after ischemia,these signs included volume enlargement and increase of signal intensity on T 2WI.On immunohistochemistry examintaion, positive plasma brown stain in neurocytes,endothelium and gliocytes in ischemic brain tissue were detected.And the stain was intensified gradually from 12h to 72h.The score of immunohistochemistry positive stain of specimen correlated with MRI signs of VBE ( r =0.820～0.994).Conclusion:VBE could be evaluated dynamically with MRI.VEGF expression of brain tissue was positive correlated with MRI signs of VBE in ischemia reperfusion model of rats." @default.
- W2377202347 created "2016-06-24" @default.
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- W2377202347 date "2003-01-01" @default.
- W2377202347 modified "2023-09-25" @default.
- W2377202347 title "MRI manifestations of vasogenic brain edema in acute ischemia reperfusion rats and VEGF expression of ischemic brain tissue" @default.
- W2377202347 hasPublicationYear "2003" @default.
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