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- W2377210427 abstract "Objective To elucidate the molecular mechanism of ABO,MNS,Duffy,Diego,Lutheran,Kidd,Dombrock and Colton blood groups in Sichuan Yi population,and investigate their gene frequencies.Methods The ABO blood group of 120 samples were genotyped through sequencing exons 6 and 7 of ABO gene,and the others were genotyped by PCR-SSP.Results In the unrelated 120 samples,five common ABO alleles were identified:A101(0.020 8),A102(0.166 7),B101(0.245 8),O01(0.304 2),O02(0.262 5).Compared to Sichuan Han population,the frequency of the A gene was significantly lower.The allele frequencies of other seven blood groups were as follows:M=0.683 3,N =0.316 7,S=0.091 7,s=0.908 3;Lua=0,Lub=1;Fya=0.945 8,Fyb=0.029 2,FyES=0.025 0;Jka=0.525 0,Jkb=0.475 0;Dia=0.016 7,Dib=0.983 3;Doa=0.120 8,Dob=0.879 2;Coa=1,Cob=0.The allele frequencies of the MNS and Diego were consistent with the data of population in the south China.The Yi population also showed the genetic specialty of their own:FyES gene exists,and the frequency of Jka gene is a little bit higher than that of Jkb gene,and the frequency of Doa gene is little bit higher.There was no differences between the gene frequencies of Lutheran and Colton blood group(they all were in accordance with Hardy-weinberg equilibrium).Conclusion This study reveals the genetic background of 9 red cell blood group systems in Sichuan Yi population,and provides scientific data for safe transfusion,blood donor recruitment and correct blood Storage." @default.
- W2377210427 created "2016-06-24" @default.
- W2377210427 creator A5084313385 @default.
- W2377210427 date "2013-01-01" @default.
- W2377210427 modified "2023-09-26" @default.
- W2377210427 title "Molecular genetic analysis of ABO,MNS,Duffy,Diego,Lutheran,Kidd,Dombrock and Colton blood group systems in Sichuan Yi population" @default.
- W2377210427 hasPublicationYear "2013" @default.
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