Matches in SemOpenAlex for { <https://semopenalex.org/work/W2377243600> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2377243600 abstract "Objective:To analyze and evaluate retrospectively the diagnostic value and clinical significance of tumor markers as CEA and CA19-9 in tumors of digestive system,all defined by pathology.Methods:The serum content of these tumor markers was measured in 272 tumors of digestive system,and 167 benign diseases with electrochemiluminescence immunoassay(ECLIA) and compared their sensitivity,specificity,accuracy,positive predictive value(PPV) and positive likelihood ratio(LR+) were analyzed.Results:The sensitivity of CEA and CA19-9 to diagnose tumors of digestive system was 34.2% and 45.2% respectively and 49.3% in combination,while the specificity was 80.8% and 60.5% respectively and 59.3% in combination.The accuracy increased from 51.9%(CEA) and 51.0%(CA19-9) to 53.1%(CEA and CA19-9).The CV of the method was less than 3%,so the repetition was good.The sensitivity of CEA to diagnose pancreatic carcinoma was highest(55.6%),and a bit higher for carcinoma of gallbladder and bile duct(41.7%) as well as colorectal carcinoma(41.6%);the specificity was highest in carcinoma of gallbladder and bile duct(88.2%) and that of liver cancer was 85.0%;the PPV of cancers of esophagus was highest(88.9%) and pancreatic carcinoma was second highest(83.3%);the LR+ was highest in carcinoma of gallbladder and bile duct(3.5).On the other hand,the sensitivity of CA19-9 to diagnose carcinoma of gallbladder and bile duct was much higher than that of any other tumor(83.3%) and that of pancreatic carcinoma and liver cancer was 77.8% and 69.8% respectively;the specificity was highest in pancreatic carcinoma and cancers of esophagus(75.0%);the PPV of pancreatic carcinoma and colorectal carcinoma was 87.5% and 75.6%;whereas the LR+ was highest in pancreatic carcinoma(3.1).Conclusion:Except for cancers of stomach and esophagus,the sensitivity of CA19-9 is higher than that of CEA.It indeed improves the sensitivity and accuracy in diagnosing tumors of digestive system by measuring CEA and CA19-9 in combination,so it is really an effective way to choose both of them to help diagnose tumors of digestive system in an early stage." @default.
- W2377243600 created "2016-06-24" @default.
- W2377243600 creator A5087375429 @default.
- W2377243600 date "2008-01-01" @default.
- W2377243600 modified "2023-09-25" @default.
- W2377243600 title "The Diagnostic Value of CEA and CA19-9 in Malignant Diseases of Digestive System" @default.
- W2377243600 hasPublicationYear "2008" @default.
- W2377243600 type Work @default.
- W2377243600 sameAs 2377243600 @default.
- W2377243600 citedByCount "0" @default.
- W2377243600 crossrefType "journal-article" @default.
- W2377243600 hasAuthorship W2377243600A5087375429 @default.
- W2377243600 hasConcept C121608353 @default.
- W2377243600 hasConcept C126322002 @default.
- W2377243600 hasConcept C142724271 @default.
- W2377243600 hasConcept C144369459 @default.
- W2377243600 hasConcept C2777148285 @default.
- W2377243600 hasConcept C2777546739 @default.
- W2377243600 hasConcept C2779777945 @default.
- W2377243600 hasConcept C2780210213 @default.
- W2377243600 hasConcept C2781447364 @default.
- W2377243600 hasConcept C2908539361 @default.
- W2377243600 hasConcept C71924100 @default.
- W2377243600 hasConcept C90924648 @default.
- W2377243600 hasConceptScore W2377243600C121608353 @default.
- W2377243600 hasConceptScore W2377243600C126322002 @default.
- W2377243600 hasConceptScore W2377243600C142724271 @default.
- W2377243600 hasConceptScore W2377243600C144369459 @default.
- W2377243600 hasConceptScore W2377243600C2777148285 @default.
- W2377243600 hasConceptScore W2377243600C2777546739 @default.
- W2377243600 hasConceptScore W2377243600C2779777945 @default.
- W2377243600 hasConceptScore W2377243600C2780210213 @default.
- W2377243600 hasConceptScore W2377243600C2781447364 @default.
- W2377243600 hasConceptScore W2377243600C2908539361 @default.
- W2377243600 hasConceptScore W2377243600C71924100 @default.
- W2377243600 hasConceptScore W2377243600C90924648 @default.
- W2377243600 hasLocation W23772436001 @default.
- W2377243600 hasOpenAccess W2377243600 @default.
- W2377243600 hasPrimaryLocation W23772436001 @default.
- W2377243600 hasRelatedWork W1996322076 @default.
- W2377243600 hasRelatedWork W2022797070 @default.
- W2377243600 hasRelatedWork W2080088210 @default.
- W2377243600 hasRelatedWork W2350430202 @default.
- W2377243600 hasRelatedWork W2351002915 @default.
- W2377243600 hasRelatedWork W2351323438 @default.
- W2377243600 hasRelatedWork W2353420407 @default.
- W2377243600 hasRelatedWork W2353845059 @default.
- W2377243600 hasRelatedWork W2363449489 @default.
- W2377243600 hasRelatedWork W2370384351 @default.
- W2377243600 hasRelatedWork W2371350382 @default.
- W2377243600 hasRelatedWork W2371759728 @default.
- W2377243600 hasRelatedWork W2373543643 @default.
- W2377243600 hasRelatedWork W2373679004 @default.
- W2377243600 hasRelatedWork W2380051132 @default.
- W2377243600 hasRelatedWork W2388487244 @default.
- W2377243600 hasRelatedWork W2391853854 @default.
- W2377243600 hasRelatedWork W2440510466 @default.
- W2377243600 hasRelatedWork W2588459838 @default.
- W2377243600 hasRelatedWork W3032226634 @default.
- W2377243600 isParatext "false" @default.
- W2377243600 isRetracted "false" @default.
- W2377243600 magId "2377243600" @default.
- W2377243600 workType "article" @default.