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- W2377281013 abstract "Objective:To study the effects of Cinnamon Twig with Six Drugs including Rehmannia Decoction on tail skin temperature(TST)、estradiol(E2)、gonadotropin releasing hormone(GnRH) andβ-endorphin(β-EP) in menopausal hot flushes rats.Methods:Adult Wistar female rats were randomly divided into four groups:normal group,model group,Chinese medicine high-and low-dose groups.Except the rats in normal group,the rats received removal of bilateral ovaries to establish menopausal rat models.All of the TST were measured and its mean values were calculated every week from first week before till 9th week after the ovariectomy.Chinese medicine group were given traditional herbal decoction by ig administration for 9 weeks.The serum E2,GnRH,β-EP levels were measured each group by enzyme-linked immunosorbent assay in the end.Result The TST of model group was elevated(P0.05) from the first till 4th week after the ovariectomy compared with that of other groups at 20℃ and it was increased(P0.05) from 5th till 9th week after the elevation of ambient temperature at 30℃.The level of GnRH was increased(P0.05) and the β-EP was decreased(P0.01) in the model group compared with those in other groups in the end.The level of serum E2 was decreased(P0.01 or P0.05) in model group and in Chinese medicine group compared with that in normal group.Conclusion the role of TCM Treatment of Reinforcing Kidney and Regulating Ying-wei was not to regulate the level of serum E2but to modulate the secretion of serum GnRH and β-EP in menopausal hot flushes rats." @default.
- W2377281013 created "2016-06-24" @default.
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- W2377281013 date "2011-01-01" @default.
- W2377281013 modified "2023-09-23" @default.
- W2377281013 title "Effect of Cinnamon Twig with Six Drugs including Rehmannia Decoction on Thermoregulation in Rats with Menopausal Hot Flushe" @default.
- W2377281013 hasPublicationYear "2011" @default.
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