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- W2377302521 abstract "Objective To study the expression of p53,nitric oxide synthase( NOS) and vascular endothelial growth fator( VEGF) and their relation with angiogenesis and prognosis of breast carcinoma. Methods The expression of p53,iNOS,eNOS and VEGF was determined with immunohistochemical meth-od( SP method) in 49 cases of breast carcinoma,and the results were analyzed with clinical manifestation and prognosis,and the cases were followed-up. Results The expression rates of p53,iNOS,eNOS and VEGF in breast carcinoma were 59. 2% ,71. 4% ,57. 1% and 49. 0% ,respectively. They were not associated with histological type( P 0. 05) ,but significantly correlated to stages and the postoperative survival time( P 0. 05) . iNOS was related to grading of breast carcinoma. Conclusion The expression of p53,NOS and VEGF has close relation to angiogenesis,growth and invasion of breast carcinoma,and postoperative survival time of the patient. They may be accepted as important markers for evaluating the prognosis of patients with breast carcinoma." @default.
- W2377302521 created "2016-06-24" @default.
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- W2377302521 date "2010-01-01" @default.
- W2377302521 modified "2023-09-24" @default.
- W2377302521 title "Expression of p53,NOS and VEGF in breast carcinoma and its clinical significance" @default.
- W2377302521 hasPublicationYear "2010" @default.
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