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- W2377303904 abstract "Objective: To explore the hypoxic status of the tissue in the course of scar formation and the influencing factors. Method: The expressions of HIF-1α and CD34 in burn wound granulation, burn scar of different phases and normal skin were detected by immunohistochemical method. The expressions of HIF-1α in epidermis and dermis were quantified by weight method and microvessel count was done on the basis of the expression of CD34. Result: As the course of scar formation and maturation developed, the expression of HIF-1α weakened, the count of microvessels and the density of dermis cells decreased gradually. Conclusion: High density and high activity of cells are important factors of the formation of hypoxic environment in scar. Amelioration of hypoxia may accelerate scar maturation. HIF-1α may play an important role in hypoxia amelioration." @default.
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- W2377303904 date "2004-01-01" @default.
- W2377303904 modified "2023-09-25" @default.
- W2377303904 title "Changes of hypoxic environment in burn scars" @default.
- W2377303904 hasPublicationYear "2004" @default.
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