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- W2377308188 abstract "Objective To investigate the relationship between plasma omentin-1 levels and inflammatory reaction and to explore relationship and significance of inflammatory protein and inflammatory cytokine in CHD patients accompanied with T2DM.Methods 28 patients with coronary heart disease(CHD),32 patients with CHD complicated by T2DM,and 26 subjects with normal control(NC) participated in this study.Fasting plasma omentin-1 levels was measured by enzyme-linked immunosorbent assay(ELISA).Interleukin-6(IL-6) and high-sensitivity C-reactive protein(hs-CRP) were measured.Comparative analysis among them was also conducted.Results Patients with CHD and CHD complicated by T2DM had significantly lower plasma omentin-1 levels and higher 1L-6 and hs-CRP than that of NC group;Patients with CHD complicated by T2DM had significantly lower plasma omentin-1 levels and higher 1L-6 and hs-CRP than that of CHD group.Fasting plasma omentin-1 levels were correlated negatively with 1L-6 and hs-CRP in patients with CHD complicated by T2DM(r=-0.353,P0.05;r=-0.581,P0.01).Hs-CRP was positively correlated with 1L-6(r=0.279,P0.05).Conclusion The abnormal expression of omentin-1,1L-6 and hs-CRP exists in patients with CHD,especially in patients with CHD complicated by T2DM.A significant correlation was found among them.omentin-1,1L-6 and hs-CRP may be involved in the development and progress of CHD complicated by T2DM,which was inconvenient for early intervention for CHD complicated by T2DM." @default.
- W2377308188 created "2016-06-24" @default.
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- W2377308188 date "2011-01-01" @default.
- W2377308188 modified "2023-09-25" @default.
- W2377308188 title "Relationship between CHD Patients Accompanied with T2DM and Plasma Omentin-1,IL-6 and hs-CRP Levels" @default.
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