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- W2377321569 abstract "Objective It is to discuss the anti-tumor function of small Radix Buppleuri decoction (SRBD) on bearing cancer mice S180 and its possible mechanism. Methods The inhibition of different concentration SRBD on sarcoma180 was observed with in vivo experiment. The apoptosis of tumor cells induced by SRBD and its influence on cell cycle were studied with flow cytometry. Results SRBD had obvious inhibition on bearing cancer mice S_(180) cell in the medium dose and small dose groups. SRBD could induce the apoptosis of bearing cancer mice S_(180) cell in every group, the difference was significant compared with control group (P0.05). In the medium dose and small dose groups, the cells quantity in S stage decreased obviously (P0.05) and that in G0/G1 stage increased obviously (P0.05), S_(180) cell proliferation index debased obviously (P0.05). Conclusion SRBD has anti-tumor effect on the growth of bearing cancer mice S_(180) cell, the mechanism may be related with inducing tumor cell apoptosis and inhibiting the proliferation cycle of tumor cells." @default.
- W2377321569 created "2016-06-24" @default.
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- W2377321569 date "2005-01-01" @default.
- W2377321569 modified "2023-09-27" @default.
- W2377321569 title "Small Radix Bupleuri decoction inducing bearing cancer mice S180 cell apoptosis and influence of it on cell cycle" @default.
- W2377321569 hasPublicationYear "2005" @default.
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