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- W2377330059 abstract "The effects of pinealectomy and exogenous melatonin(MT) on acute swelling induced by carrageenin and adjuvant arthritis in rats were investigated. It was found that pinealectomy could poteniate significantly the swelling of rats hind paw induced by injection of carrageenin and CFA in 2 h and on d 20,d 24 respectively.Exogenous MT(10μg·kg-1)could antagonize above change. MT administrated in 30min before injection of carrageenin decreased the swelling of rats hind paw in doses of(10,200, 4000μg·kg-1). Our results indicated that MT had inhibitory effect on inflammation." @default.
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- W2377330059 date "1994-01-01" @default.
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- W2377330059 title "Effects of pinealectomy and melatonin on inflammatory response" @default.
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