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- W2377335989 abstract "Aim:To observe the influence of paraquat on the expression of activin and its receptor in PC12 cells.Methods:Paraquat was added to the culture media of PC12 cells. We assayed changes of expression of activin beta A ,activin beta B,inhibin alpha and receptor ⅡA mRNAs with RT-PCR methods,and assayed the change of cell viability with tyrpan blue exclusion method. Results:The expression of activin beta A,activin beta B and activin receptor ⅡA mRNAs in PC12 cells was down-regulated significantly after the injury of paraquat,while the expression of inhibin alpha mRNA remained unchanged. The cell viability decreased at the points of 12 hours and 24 hours following the injury of paraquat. Conclusion:Paraquat might cause the injury of PC12 cells by means of down-regulating the expression of activin and its receptor." @default.
- W2377335989 created "2016-06-24" @default.
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- W2377335989 date "2005-01-01" @default.
- W2377335989 modified "2023-09-26" @default.
- W2377335989 title "The Influence of Paraquat on the Expression of Activin and Its Receptor IIA in PC12 Cells" @default.
- W2377335989 hasPublicationYear "2005" @default.
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