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- W2377351976 abstract "Objective To explore the pathological basis of the magnetic resonance imaging( MRI) features of giant cell tumors( GCTs) in the mobile spine. Methods The MRI images and pathological appearances of 21 patients with GCT were retrospectively reviewed. Results Twenty tumors showed homogeneous low to intermediate signal intensity on T1WI images and one tumor showed heterogeneous signal intensity on T1WI. 11 cases showed iso to low signal intensity on T2WI.Calcification,bone like matrix,collagen matrix and hemosiderin deposition made low signal intensity. Eight tumors showed heterogeneous signal intensity mainly due to secondary cystic changes,necrosis,and hemorrhage. Abundant mononuclear and multinucleated giant cells without calcification,bone-like matrix,collagen matrix and hemosiderin deposition made tumors as relatively high signal on T2WI. Curvilinear low signal was observed in six cases on T1WI and T2WI images within the vertebral body,which corresponded to thickened trabeculae,fibrous setae,or hemosiderin deposit. The low-signal-intensity pseudocapsule was observed in one tumor due to surrounding fibrous proliferation. Abundant thin walled capillaries,blood sinus were the basement of the enhancement pattern. Contrast enhanced scan showed significant homogeneous enhancement in six cases and nine cases showed heterogeneous enhancement due to cystic changes,necrosis. One case showed no significant enhancement due to rare thin-walled capillaries in the stroma. Conclusion MRI appearances can reflect the pathological characteristic of GCTs. The proportion of parenchyma and interstitial led to tumor signal diversity." @default.
- W2377351976 created "2016-06-24" @default.
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- W2377351976 date "2013-01-01" @default.
- W2377351976 modified "2023-09-25" @default.
- W2377351976 title "MRI Appearances of Giant Cell Tumors in the Mobile Spine:Compared with Pathology" @default.
- W2377351976 hasPublicationYear "2013" @default.
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