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- W2377393670 abstract "OBJECTIVE:To compare the healing effect of traditional therapy versus the traditional therapy in combination with additional externally applied agent on the traumatic tympanic membrane perforation with a focus on the effect of recombinant human epidermal growth factor(rhEGF) in promoting healing of tympanic membrane perforation.METHODS:A total of 90 patients with traumatic tympanic membrane perforation were randomly divided into two groups:one group received traditional therapy in which the anti-inflammatory drug was given plus nasal administration with water not allowed entering in the external acoustic meatus;another group was treated with traditional therapy plus rhEGF cotton applied externally.The healing of the tympanic membrane perforation and the auditory acuity improvement in two groups were monitored.RESULTS:In rhEGF group(58 cases),the cure rate reached 100%,with an average healing time of 5.3 days;Of the 32 cases in the traditional therapy group,7 were not failed,and 25(78%) healed,with an average healing time of 28.4 days.The healing time of tympanic membrane perforation in rhEGF group was significantly shorter than in traditional group,showing significant difference(P 0.01).The healing rates in two groups were also significantly different(P0.05).CONCLUSION:The additional external application of rhEGF can significantly shorten the healing time for tympanic membrane perforation meanwhile increasing the healing rate of the tympanic membrane perforation." @default.
- W2377393670 created "2016-06-24" @default.
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- W2377393670 date "2008-01-01" @default.
- W2377393670 modified "2023-09-25" @default.
- W2377393670 title "Recombinant Human Epidermal Growth Factor (rhEGF) in the Treatment of Traumatic Tympanic Membrane Perforation:A Clinical Study" @default.
- W2377393670 hasPublicationYear "2008" @default.
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