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- W2377506518 abstract "Objective To explore the effects of coronary artery bypass graft(CABG) surgery performed by using both standard cardiopulmonary bypass(CPB) or the octopus technique on Endothelin-1(ET-1) levels and left ventricular function. Methods Sixty-two patients undergoing CABG surgeries were randomly divided into two groups: the G1 group(n=30) which received CPB-CABG and the G2 group(n=32) which received off-pump CABG(OPCABG).Blood samples were obtained before anesthesia(T1),before operation(T2),6 h(T3) and 24 h(T4) after the end of operation.Serum Endothelin-1,CI and LVSWI were determined at each time-point.Results Serum ET-1 of the G1 group was significantly increased at T3 and T4 time-points and of the G2 group was decreased at T2 time-point and increased at T4 time-point.Serum ET-1 of the G2 group was decreased at T3 and T4 time-points compared with the G1 group(P0.05).Compared with T1 time-point,CI of the G1 group at T2 and T3 time-points and that of the G2 group at T2 time-point were markedly decreased(P0.05),and also LVSWI of the G1 group at the T3 and T4 time-points were markedly decreased(P0.05).Compared with the G1 group,CI and LVSWI of the G2 group at the T3 time-point were increased(P0.05).Conclusion Off-pump CABG can decrease the output of ET-1 and has a protective effect on myocardial injury and it is superior to CPB-CABG." @default.
- W2377506518 created "2016-06-24" @default.
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- W2377506518 date "2008-01-01" @default.
- W2377506518 modified "2023-09-23" @default.
- W2377506518 title "CABG with off-pump technique or cardiopulmonary bypass for serum Endothelin-1 and left ventricular function" @default.
- W2377506518 hasPublicationYear "2008" @default.
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