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- W2377526072 abstract "Objective:To compare the changes of immune function after laparoscopic-assisted and open radical gastrectomy for advanced gastric cancer.Methods:Laparoscopic-assisted(n=47)and open(n=47)radical gastrectomy for advanced gastric cancer was performed.IL-6、CRP、IgG 、IgM 、IgA 、CD3+、CD4+、CD8+、CD4+/CD8+、 HLA-DR、 PMN were tested before operation and after operation for 3,7 and 14 days.Results:On the day 3 postoperatively,IgG、 IgM、IgA significantly decreased as compared with those preoperatively in two groups(P0.05).In open group,IgG 、IgM 、IgA decreased as compared to those preoperatively on the day 7 postoperatively(P0.05).In Laparoscope-assisted group,there were significant differences of IgG 、IgM 、IgA between before and after operation(P0.05).The levels of IgA and IgG showed no statistical difference after operation in both groups(P0.05).On the day 3,7 postoperatively,IL-6 and CRP significantly increased as compared to those preoperatively in two groups(P0.01),and the parameters in Laparoscope-assisted group were all singnificantly high than those in open group(P0.01).In two groups,HLA-DR increased postoperative as compared to preoperatively(P0.01),and there were significant differences of HLA-DR between two groups on the day 3、7 and 14 postoperatively(P0.01),PMN increased after operation 3rd day in two groups(P0.01),On the day 7,14 postoperatively,the levels of CD3+、CD4+ and the ratio of CD4+/CD8+ significantly decreased as compared to those preoperatively in two groups(P0.01),the parameters in Laparoscope-assisted group were all singnificantly high than those in open group(P0.01).Conclusion:Laparoscopic-assisted radical gastrectomy resulted in a lesser depression to the immune system and a quicker recovery." @default.
- W2377526072 created "2016-06-24" @default.
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- W2377526072 date "2009-01-01" @default.
- W2377526072 modified "2023-09-26" @default.
- W2377526072 title "Clinical comparison of immune response after laparoscope-assisted and open radical operation for advanced gastric cancer" @default.
- W2377526072 hasPublicationYear "2009" @default.
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