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- W2377526369 abstract "Objective:To apply different combinations of antiemetic drugs to determine concentration changes of serum 5-HT of patients undergoing laparoscopic gallbladder surgery and to observe nausea and vomiting state after 24 hours and to explore how the combined application of three kinds of antiemetic drugs would influence high vomiting risk female patients after laparoscopic cholecystectomy in serum 5-HT and post-operative nausea and vomiting.Methods:To operate laparoscopic cholecystectomy(LC) on 60 female patients,divided into three groups of 20 each.Patients of the first group were given ondansetron;those of the second were given ondansetron with dexamethasone;Ondansetron with dexameth asone and droperidol were given tothose of the third group.Taken 5ml radial vein respectively at 4 time points.Results:For postoperative nausea and vomiting,the third group was obviously different from the first and second one(P0.05);while at T1,T2 and T3,5-HT concentrations of the third group was lower than the other two groups and differences were significant(P0.05).Conclusion:The clinical effect was positive when applying three kinds of antiemetic drugs in combination to prevent high risk vomiting patients from postoperative nausea and vomiting in laparoscopic cholecystectomy.They greatly reduced the incidence of PONV with the lightest adverse reactions after abdominal surgery.They might be much better than the single drug application." @default.
- W2377526369 created "2016-06-24" @default.
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- W2377526369 date "2011-01-01" @default.
- W2377526369 modified "2023-09-24" @default.
- W2377526369 title "Clinical Obseration on Combination Use of Antiemetic Druge to Prevent Nausea and Vommiting after General Anesthesia" @default.
- W2377526369 hasPublicationYear "2011" @default.
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