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- W2377527404 abstract "This study is to explore the changes of human mitochondrial Cyt b,ATPase 6 and ATPase 8 genes expression induced by 60Co γ-rays irradiation. The dose-effect relationships between expression changes of the genes and the absorbed doses were analyzed by RT-PCR (Reverse Transcription PCR) and Real-time PCR at 8 h after the irradiation in human lymphoblastoid cell lines,which were exposed to 1—10 Gy 60Co γ-rays. The changes of these genes expression were also analyzed at different post-radiation time-points between 0.5 h and 72 h after irradiation of 5 Gy to explore the time-effect relationships. The results showed that the expression of 3 genes were up-regulated comprehensively. A good dose-effect relationship was showed for Cyt b and ATPase 8 at dose range of 0—8 Gy. For the time-effect after irradiation,the expression levels of 3 genes were up-regulated generally and the peak change time-point was 4 h after irradiation. 60Co γ-rays irradiation might induce the changes of mitochondrial Cyt b,ATPase 6 and ATPase 8 genes expression,and these genes expression are up-regulated generally." @default.
- W2377527404 created "2016-06-24" @default.
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- W2377527404 date "2010-01-01" @default.
- W2377527404 modified "2023-09-25" @default.
- W2377527404 title "Detection of the expression changes of human mitochondrial Cyt b,ATPase 6 and ATPase 8 genes induced by ~(60)Coγ-rays" @default.
- W2377527404 hasPublicationYear "2010" @default.
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