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- W2377541885 abstract "[Objective]To study the therapeutic effect of Sanhuang decoction on ulcerative colitis(UC)rats induced by trinitrobenzene sulphoacid(TNBS).[Methods]Forty-five UC rats were induced by TNBS and randomly divided into model group,positive control group and Sanhuang decoction group,with 15 rats in each group.Fifteen normal Wistar rats were set as control group.Model group and normal control group were treated by 0.9% sodium chloride injection,positive control group by Salazosulfapyridine(SASP)(0.5 g/kg),Sanhuang decoction group by Sanhuang decoction respectively(60 g/kg),once per day.The treatment was given from the 3rd day after modeling for consecutive 7 days.Changes of CMDI,mucous membrane histopathology were observed on the 11st day.[Results]Compared with model control and positive control groups,CMDI and pathologic injury were markedly improved in Sanhuang decoction group.[Conclusion]Sanhuang decoction is effective in the treatment of UC rats induced by TNBS,ameliorating the congestion,edema,ulcers,erosion of the colonic mucosa." @default.
- W2377541885 created "2016-06-24" @default.
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- W2377541885 date "2010-01-01" @default.
- W2377541885 modified "2023-09-28" @default.
- W2377541885 title "Therapeutic effect of Sanhuang decoction on ulcerative colitis rats" @default.
- W2377541885 hasPublicationYear "2010" @default.
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