Matches in SemOpenAlex for { <https://semopenalex.org/work/W2377591479> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2377591479 abstract "Objective To investigate the effect of intraperitoneal endostar administration to treat H22 ascites in mice.Methods A mouse model of ascites was established by inoculating 110 Kunming mice with H22 cells(2×106,i.p.injection).Mice were then divided randomly into 5 groups:control(normal saline);low endostar dose(4 mg/kg·day),intermediate endostar dose(8 mg/kg·day),high endostar dose(12 mg/kg·day)and positive control(DDP 0.6 mg/kg·day).After an adjustment period of 24h,the groups were treated from day 1 to day 10 by i.p.injection as indicated above and sacrificed 24h after drug withdrawal.Data were collected on volume of ascitic fluid,metastases of abdominal organs and lungs and survival time.Peritoneal membrane permeability was assessed using Evan blue staining.Results Intermediate and high doses of endostar significantly inhibited the production of ascites in H22 ascitesbearing mice,reduced the frequency of metastases in the abdominal viscera and lungs,and lengthened average survival time.Conclusion Intraperitoneal administration of endostar can reduce ascites in H22 ascites-bearing mice." @default.
- W2377591479 created "2016-06-24" @default.
- W2377591479 creator A5059072776 @default.
- W2377591479 date "2012-01-01" @default.
- W2377591479 modified "2023-09-26" @default.
- W2377591479 title "Ability of recombinant human endostatin to reduce H22 ascites in mice" @default.
- W2377591479 hasPublicationYear "2012" @default.
- W2377591479 type Work @default.
- W2377591479 sameAs 2377591479 @default.
- W2377591479 citedByCount "0" @default.
- W2377591479 crossrefType "journal-article" @default.
- W2377591479 hasAuthorship W2377591479A5059072776 @default.
- W2377591479 hasConcept C126322002 @default.
- W2377591479 hasConcept C141071460 @default.
- W2377591479 hasConcept C142724271 @default.
- W2377591479 hasConcept C2776001837 @default.
- W2377591479 hasConcept C2777397205 @default.
- W2377591479 hasConcept C2778536324 @default.
- W2377591479 hasConcept C2780159080 @default.
- W2377591479 hasConcept C2780496750 @default.
- W2377591479 hasConcept C2780936613 @default.
- W2377591479 hasConcept C71924100 @default.
- W2377591479 hasConcept C98274493 @default.
- W2377591479 hasConceptScore W2377591479C126322002 @default.
- W2377591479 hasConceptScore W2377591479C141071460 @default.
- W2377591479 hasConceptScore W2377591479C142724271 @default.
- W2377591479 hasConceptScore W2377591479C2776001837 @default.
- W2377591479 hasConceptScore W2377591479C2777397205 @default.
- W2377591479 hasConceptScore W2377591479C2778536324 @default.
- W2377591479 hasConceptScore W2377591479C2780159080 @default.
- W2377591479 hasConceptScore W2377591479C2780496750 @default.
- W2377591479 hasConceptScore W2377591479C2780936613 @default.
- W2377591479 hasConceptScore W2377591479C71924100 @default.
- W2377591479 hasConceptScore W2377591479C98274493 @default.
- W2377591479 hasLocation W23775914791 @default.
- W2377591479 hasOpenAccess W2377591479 @default.
- W2377591479 hasPrimaryLocation W23775914791 @default.
- W2377591479 hasRelatedWork W2060063916 @default.
- W2377591479 hasRelatedWork W2353402185 @default.
- W2377591479 hasRelatedWork W2354189070 @default.
- W2377591479 hasRelatedWork W2359170993 @default.
- W2377591479 hasRelatedWork W2362960875 @default.
- W2377591479 hasRelatedWork W2366271449 @default.
- W2377591479 hasRelatedWork W2368868365 @default.
- W2377591479 hasRelatedWork W2371221349 @default.
- W2377591479 hasRelatedWork W2372472785 @default.
- W2377591479 hasRelatedWork W2379856119 @default.
- W2377591479 hasRelatedWork W2383037581 @default.
- W2377591479 hasRelatedWork W2384120296 @default.
- W2377591479 hasRelatedWork W2385410762 @default.
- W2377591479 hasRelatedWork W2388762021 @default.
- W2377591479 hasRelatedWork W2392175189 @default.
- W2377591479 hasRelatedWork W2393951223 @default.
- W2377591479 hasRelatedWork W2404733004 @default.
- W2377591479 hasRelatedWork W3030345644 @default.
- W2377591479 hasRelatedWork W3031463911 @default.
- W2377591479 hasRelatedWork W1824085087 @default.
- W2377591479 isParatext "false" @default.
- W2377591479 isRetracted "false" @default.
- W2377591479 magId "2377591479" @default.
- W2377591479 workType "article" @default.