Matches in SemOpenAlex for { <https://semopenalex.org/work/W2377647788> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2377647788 abstract "Objective:To investigate T lymphocyte subsets in peripheral blood from patients with lung carcinoma,and its clinical significance.Methods:The lymphocyte subsets in peripheral blood from 56 lung cancer patients and 18 healthy controls were measured via direct immunofluorescent assay by flow cytometry.The lymphocyte subsets include total T cells(CD3+),Th cells(CD3+CD4+),Tc cells(CD3+CD8+),NKT cells(CD3+CD16+CD56+),NK cells(CD3-CD16+CD56+),regulatory T cells(CD4+CD25+Foxp3+)and CD3+γδT+ cells.Results:The amount of total T cells(CD3+)in the PBMC of the patients with lung cancer was significantly decreased than that of healthy individuals(61.41%±7.88% vs 71.63%±5.59%,P0.001).The ratio of Tc of patients with lung cancer was significantly lower than that of healthy individuals(23.58±7.18% vs 28.44%±5.20%,P0.05).The ratio of Treg(CD4+CD25+Foxp3+)in patients with lung cancer was significantly increased than that of healthy individuals(6.20%±1.635% vs 3.65%±2.00%,P0.001).The ratio of CD3+γδT+ cell in PBMC of lung cancer patients was significantly lower than that of healthy individuals(3.35%±1.41% vs 5.53%±1.87%,P0.01).The ratio of NK in PBMC of lung cancer patients was significantly lower than that of healthy individual(15.02%±7.61% vs 18.74%±6.39%,P0.05).The ratio of γδT cells has a significantly statistics difference between the early-middle stage of lung carcinoma and later stage of lung carcinoma(3.70%±1.89% vs 2.64%±1.41%,P0.05).The ratio of Treg cells has a significantly statistics difference between the early-middle stage of lung carcinoma and later stage of lung carcinoma(6.78%±2.64% vs 5.06%±1.22%,P0.05).The amount of Th and NKT cells in PBMC decreased in lung cancer patients,but they didn't had statistics difference(P0.05).Conclusion:Total T cells,Th,Tc,NK cells in PBMC of the patients with lung cancer decrease and Treg increase.This suggests that the patients with lung cancer are in immune suppressed statue.Treg and γδT cell have some kind of relevance with the clinical process of lung cancer." @default.
- W2377647788 created "2016-06-24" @default.
- W2377647788 creator A5044639756 @default.
- W2377647788 date "2010-01-01" @default.
- W2377647788 modified "2023-09-25" @default.
- W2377647788 title "The clinical significance of T lymphocyte subsets in peripheral blood from patients with lung carcinoma" @default.
- W2377647788 hasPublicationYear "2010" @default.
- W2377647788 type Work @default.
- W2377647788 sameAs 2377647788 @default.
- W2377647788 citedByCount "0" @default.
- W2377647788 crossrefType "journal-article" @default.
- W2377647788 hasAuthorship W2377647788A5044639756 @default.
- W2377647788 hasConcept C114684123 @default.
- W2377647788 hasConcept C126322002 @default.
- W2377647788 hasConcept C137061746 @default.
- W2377647788 hasConcept C167672396 @default.
- W2377647788 hasConcept C202751555 @default.
- W2377647788 hasConcept C203014093 @default.
- W2377647788 hasConcept C2776090121 @default.
- W2377647788 hasConcept C2776256026 @default.
- W2377647788 hasConcept C2777546739 @default.
- W2377647788 hasConcept C2777714996 @default.
- W2377647788 hasConcept C2777761686 @default.
- W2377647788 hasConcept C2779727006 @default.
- W2377647788 hasConcept C553184892 @default.
- W2377647788 hasConcept C55493867 @default.
- W2377647788 hasConcept C71924100 @default.
- W2377647788 hasConcept C79484868 @default.
- W2377647788 hasConcept C86803240 @default.
- W2377647788 hasConcept C8891405 @default.
- W2377647788 hasConcept C90924648 @default.
- W2377647788 hasConceptScore W2377647788C114684123 @default.
- W2377647788 hasConceptScore W2377647788C126322002 @default.
- W2377647788 hasConceptScore W2377647788C137061746 @default.
- W2377647788 hasConceptScore W2377647788C167672396 @default.
- W2377647788 hasConceptScore W2377647788C202751555 @default.
- W2377647788 hasConceptScore W2377647788C203014093 @default.
- W2377647788 hasConceptScore W2377647788C2776090121 @default.
- W2377647788 hasConceptScore W2377647788C2776256026 @default.
- W2377647788 hasConceptScore W2377647788C2777546739 @default.
- W2377647788 hasConceptScore W2377647788C2777714996 @default.
- W2377647788 hasConceptScore W2377647788C2777761686 @default.
- W2377647788 hasConceptScore W2377647788C2779727006 @default.
- W2377647788 hasConceptScore W2377647788C553184892 @default.
- W2377647788 hasConceptScore W2377647788C55493867 @default.
- W2377647788 hasConceptScore W2377647788C71924100 @default.
- W2377647788 hasConceptScore W2377647788C79484868 @default.
- W2377647788 hasConceptScore W2377647788C86803240 @default.
- W2377647788 hasConceptScore W2377647788C8891405 @default.
- W2377647788 hasConceptScore W2377647788C90924648 @default.
- W2377647788 hasLocation W23776477881 @default.
- W2377647788 hasOpenAccess W2377647788 @default.
- W2377647788 hasPrimaryLocation W23776477881 @default.
- W2377647788 hasRelatedWork W2091041835 @default.
- W2377647788 hasRelatedWork W2350688961 @default.
- W2377647788 hasRelatedWork W2350949157 @default.
- W2377647788 hasRelatedWork W2354539122 @default.
- W2377647788 hasRelatedWork W2359780968 @default.
- W2377647788 hasRelatedWork W2361605299 @default.
- W2377647788 hasRelatedWork W2362494702 @default.
- W2377647788 hasRelatedWork W2363505720 @default.
- W2377647788 hasRelatedWork W2380111994 @default.
- W2377647788 hasRelatedWork W2389988040 @default.
- W2377647788 hasRelatedWork W2390453215 @default.
- W2377647788 hasRelatedWork W2414809083 @default.
- W2377647788 hasRelatedWork W2768744673 @default.
- W2377647788 hasRelatedWork W3029157423 @default.
- W2377647788 hasRelatedWork W3029191989 @default.
- W2377647788 hasRelatedWork W3031829407 @default.
- W2377647788 hasRelatedWork W3031988208 @default.
- W2377647788 hasRelatedWork W3032629411 @default.
- W2377647788 hasRelatedWork W3032714336 @default.
- W2377647788 hasRelatedWork W3147642787 @default.
- W2377647788 isParatext "false" @default.
- W2377647788 isRetracted "false" @default.
- W2377647788 magId "2377647788" @default.
- W2377647788 workType "article" @default.