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- W2377763713 abstract "Diabetes mellitus and its associated micro-and macrovascular complications have posed a great threat to public health and become the main cause of morbidity and mortality burden to state economy.Recent studies have raised that epigenetics may play an important role in the pathology of diabetic vascular diseases,which refers to phenotype changes that are not related to the underlying DNA sequence,yet the alterations in gene expression can possibly be inherited into next generation. Furthermore,UKPDS and DCCT-EDIC demonstrate a phenomenon called metabolic memory,even if the blood glucose level is controlled in an ideal state,vascular inflammation still persists.Although epigenetics has not been fully elucidated,it provides a new insight into the pathogenesis of diabetes and is expected to become the targeted therapy for severe diseases." @default.
- W2377763713 created "2016-06-24" @default.
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- W2377763713 date "2014-01-01" @default.
- W2377763713 modified "2023-09-24" @default.
- W2377763713 title "Epigenetic phenomenon in diabetic vascular diseases" @default.
- W2377763713 hasPublicationYear "2014" @default.
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