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- W2377767284 abstract "Objective:To investigate the endocrine and metabolic differences between polycystic ovary syndrome (PCOS) with nonalcoholic fatty liver disease(NAFLD) and without NAFLD.Methods:Body mass index(BMI),waist-to-hip ratio(WHR),blood pressure (BP),uric acid (UA),alanine transaminase (ALT),cortiso1 (F),follicle stimulating hormone (FSH),prolactin (PRL),testosterone(T),estradiol(E2),luteinizing hormone(LH),total cholesterol(TC),triglyceride(TG),low density lipoprotein-cholesterol(LDL-C),high density lipoprotein-cholesterol(HDL-C),lipoprotein a[LP(a)],fasting blood glucose(FBG),fasting serum insulin(FINS) and leptin(LEP) levels were measured in PCOS with NAFLD group(PCOS1 group,total number is 27) and PCOS without NAFLD (PCOS2 group,total number is 23).The HOMA-IR was measured too.Results:BMI,WHR,ALT,TG,LP (a),FINS,LEP were lower while HDL-C,F were higher in PCOS2 group than those in PCOS1 group (P 0.05).HOMA-IR was positively correlated to LEP,BMI,Lp(a) in PCOS1 group,whereas HOMA-IR was positively correlated to T in PCOS2 group.Conclusion:Insulin resistance and dyslipidemia were more frequently observed in PCOS with NAFLD,while PCOS without NAFLD was demonstrated with higher T level.It is definitely that there are a clinical association between PCOS and NAFLD.The intervention and treatment of PCOS should be adopted differently between PCOS with NAFLD and PCOS without NAFLD patients." @default.
- W2377767284 created "2016-06-24" @default.
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- W2377767284 date "2010-01-01" @default.
- W2377767284 modified "2023-09-25" @default.
- W2377767284 title "Effect of polycystic ovary syndrome with or without nonalcoholic fatty liver disease on the metabolism parameters" @default.
- W2377767284 hasPublicationYear "2010" @default.
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