Matches in SemOpenAlex for { <https://semopenalex.org/work/W2377774585> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2377774585 endingPage "88" @default.
- W2377774585 startingPage "88" @default.
- W2377774585 abstract "Objective. The objective of this study is to assess whether genetic functional variants of disintegrin and metalloprotease 33 (ADAM33) are associated with susceptibility to systemic lupus erythematosus (SLE) in a Korean population. Methods. We pre- viously identified 48 single nucleotide polymorphisms (SNPs) in ADAM33. Six SNPs were selected with regard to the linkage disequilibrium pattern. An association study of ADAM33 was conducted in 190 patients with SLE and 469 control subjects. SNPs were genotyped using the TaqMan Real-time polymerase chain reaction method, and haplotype analyses of related var- iants were performed. Results. All SNPs were in Hardy-Weinberg equilibrium. Significant associations were found between the ADAM33 polymorphisms and SLE at rs2787094 (adjusted odds ratio (OR) 1.88, 95% confidence interval (CI) 1.00 to 3.54; p< 0.0001). The rs554743 polymorphism was associated with the presence of the immunoglobulin M anti-cardiolipin antibody (adjusted OR 0.29, 95% CI 0.10 to 0.83; p=0.021). Conclusion. ADAM33 polymorphisms were associated with susceptibility to SLE and development of clinical disease manifestations in a Korean population. Further study is warranted to clarify the role of ADAM33 in SLE pathogenesis. (J Rheum Dis 2016;23:88-95)" @default.
- W2377774585 created "2016-06-24" @default.
- W2377774585 creator A5005480643 @default.
- W2377774585 creator A5013542315 @default.
- W2377774585 creator A5036999579 @default.
- W2377774585 creator A5046129212 @default.
- W2377774585 creator A5050527127 @default.
- W2377774585 creator A5051212046 @default.
- W2377774585 creator A5056400066 @default.
- W2377774585 creator A5070322970 @default.
- W2377774585 date "2016-01-01" @default.
- W2377774585 modified "2023-09-24" @default.
- W2377774585 title "<i>ADAM33</i>Polymorphisms Are Associated with Susceptibility to Systemic Lupus Erythematosus in a Korean Population" @default.
- W2377774585 cites W1489601058 @default.
- W2377774585 cites W1552738427 @default.
- W2377774585 cites W1576953744 @default.
- W2377774585 cites W1935239049 @default.
- W2377774585 cites W1963577745 @default.
- W2377774585 cites W1970353663 @default.
- W2377774585 cites W1978832332 @default.
- W2377774585 cites W1981148940 @default.
- W2377774585 cites W1983995459 @default.
- W2377774585 cites W1989228411 @default.
- W2377774585 cites W1994489347 @default.
- W2377774585 cites W200675204 @default.
- W2377774585 cites W2014260674 @default.
- W2377774585 cites W2016954412 @default.
- W2377774585 cites W2022391508 @default.
- W2377774585 cites W2025112934 @default.
- W2377774585 cites W2036943040 @default.
- W2377774585 cites W2039146429 @default.
- W2377774585 cites W2061053690 @default.
- W2377774585 cites W2063014521 @default.
- W2377774585 cites W2064731204 @default.
- W2377774585 cites W2070527591 @default.
- W2377774585 cites W2085370249 @default.
- W2377774585 cites W2090938663 @default.
- W2377774585 cites W2101907901 @default.
- W2377774585 cites W2126142158 @default.
- W2377774585 cites W2139039160 @default.
- W2377774585 cites W2146203649 @default.
- W2377774585 cites W2146764660 @default.
- W2377774585 cites W2148300648 @default.
- W2377774585 cites W2152348310 @default.
- W2377774585 doi "https://doi.org/10.4078/jrd.2016.23.2.88" @default.
- W2377774585 hasPublicationYear "2016" @default.
- W2377774585 type Work @default.
- W2377774585 sameAs 2377774585 @default.
- W2377774585 citedByCount "0" @default.
- W2377774585 crossrefType "journal-article" @default.
- W2377774585 hasAuthorship W2377774585A5005480643 @default.
- W2377774585 hasAuthorship W2377774585A5013542315 @default.
- W2377774585 hasAuthorship W2377774585A5036999579 @default.
- W2377774585 hasAuthorship W2377774585A5046129212 @default.
- W2377774585 hasAuthorship W2377774585A5050527127 @default.
- W2377774585 hasAuthorship W2377774585A5051212046 @default.
- W2377774585 hasAuthorship W2377774585A5056400066 @default.
- W2377774585 hasAuthorship W2377774585A5070322970 @default.
- W2377774585 hasConcept C16005928 @default.
- W2377774585 hasConcept C203014093 @default.
- W2377774585 hasConcept C2908647359 @default.
- W2377774585 hasConcept C54355233 @default.
- W2377774585 hasConcept C71924100 @default.
- W2377774585 hasConcept C86803240 @default.
- W2377774585 hasConcept C99454951 @default.
- W2377774585 hasConceptScore W2377774585C16005928 @default.
- W2377774585 hasConceptScore W2377774585C203014093 @default.
- W2377774585 hasConceptScore W2377774585C2908647359 @default.
- W2377774585 hasConceptScore W2377774585C54355233 @default.
- W2377774585 hasConceptScore W2377774585C71924100 @default.
- W2377774585 hasConceptScore W2377774585C86803240 @default.
- W2377774585 hasConceptScore W2377774585C99454951 @default.
- W2377774585 hasFunder F4320322034 @default.
- W2377774585 hasFunder F4320322107 @default.
- W2377774585 hasIssue "2" @default.
- W2377774585 hasLocation W23777745851 @default.
- W2377774585 hasOpenAccess W2377774585 @default.
- W2377774585 hasPrimaryLocation W23777745851 @default.
- W2377774585 hasRelatedWork W1541773261 @default.
- W2377774585 hasRelatedWork W2003264273 @default.
- W2377774585 hasRelatedWork W2008996762 @default.
- W2377774585 hasRelatedWork W2128434532 @default.
- W2377774585 hasRelatedWork W2738981461 @default.
- W2377774585 hasRelatedWork W290528026 @default.
- W2377774585 hasRelatedWork W3105072830 @default.
- W2377774585 hasRelatedWork W3207681163 @default.
- W2377774585 hasRelatedWork W4234833016 @default.
- W2377774585 hasRelatedWork W4297184974 @default.
- W2377774585 hasVolume "23" @default.
- W2377774585 isParatext "false" @default.
- W2377774585 isRetracted "false" @default.
- W2377774585 magId "2377774585" @default.
- W2377774585 workType "article" @default.