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- W2377776426 abstract "Objective To investigate the expression of E-cadherin and nm23-H1 and their correlation with the invasion and metastasis of pancreatic cancer.Methods Immunohistochemical technique was used to detect the expression of E-cadherin and nm23-H1 in 31 cases of pancreatic cancer,8 normal pancreatic tissues and 7 cases of chronic pancreatitis.Invasion,metastasis and differentiation and staging in pancreatic cancer were analyzed.Results In 31 cases of pancreatic cancer,the expression levels of E-cadherin and nm23-H1 were lower than in the control tissues(P0.05).The expression intensity of E-cadherin and nm23-H1 was significantly positively correlated with the distant metastasis of pancreatic cancer.In pancreatic cancer,there was a significantly positive correlation between the expression of E-cadherin and nm23-H1.Conclusion The expression of E-cadherin and nm23-H1 can reveal the invasion and metastasis ability of pancreatic cancer.Combined detection of the E-cadherin and nm23-H1 protein expression in pancreatic cancer tissues may play some roles in clinically evaluating the the prognosis of pancreatic cancer." @default.
- W2377776426 created "2016-06-24" @default.
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- W2377776426 date "2008-01-01" @default.
- W2377776426 modified "2023-09-23" @default.
- W2377776426 title "The expression of E-cadherin and nm23-H1 in pancreatic cancer and its clinical significance" @default.
- W2377776426 hasPublicationYear "2008" @default.
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