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- W2377822397 abstract "Objective To investigate the difference of clinical and biochemical characteristics between the senile latent autoimmune diabetes in adults( LADA) and elderly type 2 diabetic patients.Methods 142 cases of elderly patients with diabetes screened by glutamic acid decarboxylase autoantibodies (GAD-Ab) were divided into two groups,17 cases in GAD-Ab positive group and 125 cases in GAD-Ab negative group.Blood biochemical detection and clinical characteristics were compared between two groups.Results There were no differences in age、sex、FPG、PBG、HbA1c、fasting insulin 、TG and TC levels 、insulin sensitivity index between the two groups(P0.05).Fasting C peptide levels were lower in GAD-Ab positive group(P0.05).No difference was found in the prevalence of coronary heart disease、hypertension、cerebral infarction and urine Alb/Cr elevation between two groups.There is positive correlation between triglyceride levels and the fasting C peptide levels in senile diabetes patients.There is negative correlation between fasting plasm glucose and the fasting C peptide levels.Conclusion Senile LADA was characterized by a similar clinical manifestation to senile T2DM. GAD-Ab detection is necessary for the diagnosis of senile LADA." @default.
- W2377822397 created "2016-06-24" @default.
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- W2377822397 date "2008-01-01" @default.
- W2377822397 modified "2023-09-24" @default.
- W2377822397 title "Significance of detection of glutamic acid decarboxylase autoantibodies in elderly patients with diabetes" @default.
- W2377822397 hasPublicationYear "2008" @default.
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