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- W2377884983 abstract "Objective To explore the effect of sulfur dioxide(SO2) on pulmonary artery pressure of rats with abdominal aorta and inferior vena cava shunting surgery with the help of detection of pulmonary artery systolic pressure(PASP) pulmonary artery,mean pressure(PAMP) and pulmonary artery diastolic pressure(PADP). Methods To explore the effect of SO2 on pulmonary artery pressure of rats with abdominal aorta and inferior vena cava shunting surgery with the help of detection of PASP,PAMP and PADP.A total of 25 male Sprague Dawley rats were divided randomly into the following groups:control group,shunting group and shunting plus SO2 donor group.For rats of shunting group and shunting plus SO2 group,an abdominal aorta and inferior vena cava shunting was created.Na2SO3/NaHSO3 was administrated intraperitoneally to rats of shunting plus SO2 group.After 8-week shunting,PASP,PAMP and PADP of each rats were evaluated by using a right cardiac catheterization procedure. Results Compared with control group,the PASP of rats in shunting group was increased significantly [(3.91±0.66) kPa vs(2.26±0.47) kPa,P0.05];Compared with shunting group,the PASP of rats in shunting plus SO2 donor group was decreased significantly [(3.04±0.36) kPa vs(3.91±0.66) kPa,P0.05];The PASP of rats in shunting plus SO2 donor group was higher than that of rats in control group [(3.04±0.36) kPa vs(2.26±0.47) kPa,P0.05].Compared with control group,the PADP of rats in shunting group was increased significantly [(1.81±0.45) kPa vs(1.26±0.32) kPa,P0.05];There was no difference between the PADP of rats in the shunting group and shunting plus SO2 donor group [(1.49±0.19) kPa vs(1.81±0.45) kPa,P0.05].Compared with control group,the PAMP of rats in shunting group was increased significantly [(2.53±0.43) kPa vs(1.60±0.36) kPa,P0.05];Compared with shunting group,the PAMP of rats in shunting plus SO2 donor group was decreased significantly [(2.01±0.23) kPa vs(2.53±0.43) kPa,P0.05];The PAMP of rats in shunting plus SO2 donor group was higher than that of rats in control group[(2.01±0.23) kPa vs(1.60±0.36) kPa,P0.05]. Conclusions SO2 obviously decreases the PAMP and PASP of rats with abdominal aorta and inferior vena cava shunting." @default.
- W2377884983 created "2016-06-24" @default.
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- W2377884983 date "2012-01-01" @default.
- W2377884983 modified "2023-09-24" @default.
- W2377884983 title "Effect of Sulfur Dioxide on Pulmonary Artery Pressure in Rats with Experimental Abdominal Aorta and Inferior Vena Cava Shunting" @default.
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