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- W2377885803 abstract "Objective To investigate drug resistance and antimicrobial combination against 38 strains of methicil-lin -resistant Staphylococci aureus(MRSA) isolated from intensive care unit(ICU) patients,so as to select rational antimicrobial agents to treat MRSA infection.Methods The isolates were identified by VITEK-2 automatic bacterial identification system and Staphylococcus aureus latex coagulation method.MRSA were detected with Staphylococcus aureus latex coagulation method.Drug susceptibility tests were performed with micro-broth dilution method based on Clinical and Laboratory Standards Institute(CLSI) Standard.Results Thirty-eight MRSA stains were sensitive to linezolid(LZD).vancomycin(VAN),and teicoplanin(TEC);the resistant rate to levofloxacin(LVX) and rifampicin(RIF) was 100.00%and 78.95%respectively.The fractional inhihitional concentration(FIC)l of RIF combining with LZD.VAN and TEC was 13.16%-31.58%:The FIC1 of LVX combining with LZD.VAN and TEC was 2.63%- 36.84%.the difference between antimicrobial combination had statistical significance(P0.01).Conclusion Rational choice of antimicrobial agents to treat MRSA infection in ICU patients should be according to antimicrobial agents and patients' state." @default.
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- W2377885803 date "2011-01-01" @default.
- W2377885803 modified "2023-09-23" @default.
- W2377885803 title "Drug resistance and antimicrobial combination against methicillin-resistant Staphylococcus aureus isolated from ICU patients" @default.
- W2377885803 hasPublicationYear "2011" @default.
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