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- W2377885814 abstract "Objective To analyze the imaging findings and pathological features of peripheral primitive neuroectodermal tumor(pPNET) of spinal column.Methods Sixteen patients of spinal pPNET underwent imaging examination,including plain(n=16) and contrast enhanced CT(n=12),as well as plain(n=14) and contrast enhanced MRI(n=9).The imaging and pathological characteristics of pPNET were analyzed retrospectively.Results The lesions located in cervical(n=7),cervicothoracic(n=1),thoracic(n=1) or lumbosacral spine(n=6),while lesions of one patient located in multiple spines.Vertebral body(n=1),vertebral body and appendix(n=10),intraspine(n=2) and paravertabral tissues(n=3) were involved.All the lesions manifested infiltration,while pathological compression fractures and internal calcification were detected in 5 patients,respectively.No disk involvement,periosteum reaction nor tumor bone was displayed.CT showed osteolytic,osteoblastic and mixed bone destruction with surrounding soft tissue masses.MR displayed mixed signals on T1WI and T2WI,which enhanced asymmetrically,meanwhile,necrosis,cystic degeneration areas and rich blood supply of soft tissue masses were found.Immunohistochemistry showed distinctive expression of CD99 and expression of other neuroendocrine markers,such as NSE,Syn and CgA.Conclusion Spinal pPNET has some imaging characteristics.CT and MRI can show the size,internal structure,extent and adjacent structure of the tumors,therefore they are being helpful to the differentiating diagnosis,but the final diagnosis still depends on pathological examination." @default.
- W2377885814 created "2016-06-24" @default.
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- W2377885814 date "2011-01-01" @default.
- W2377885814 modified "2023-09-25" @default.
- W2377885814 title "Imaging findings and pathological analysis of spinal peripheral primitive neuroectodermal tumor" @default.
- W2377885814 hasPublicationYear "2011" @default.
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