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- W2377886932 abstract "Objective: The effects of Leonurus heterophyllus sweet injection was observed by blood rheology, platelet aggregation and extrasomatic thrombosis in rat with myocardial ischemia. Methods: An animal model of myocardial ischemia was reconstructed by ligaturing the left ventricular branch of coronary artery of rat. At the first hour after myocardial ischemia, Leonurus heterophylLus sweet was injected into caudal vein and blood specimen was collected from carotid at the second hour after myocardial ischemia so as to be detected. Results: Leonurus heterophylLus sweet reduced the blood viscosity, plasma viscosity, ery-throcyte sedimentation rate (ESR) and the content of fibrinogen in plasma which augmented during myocardial ischemia (P0.05-0.01 compared with contrast), besides this, it also lowered platelet aggregation rate induced by adenosine diphosphate (ADP) and collagen respectively ( P 0. 05- 0. 01 compared with contrast). In addition, extrasomatic thrombosis was inhibited, which showed as shortened length, light wet weight and dry weight of thrombi ( P 0. 05-0. 01 compared with contrast). Conclusion: Leonurus heterophyllus sweet can improve blood rheology, inhibite platelet aggregation and extrasomatic thrombosis, so it has the effect of resistance to myocardial ischemia even to thrombotic disease." @default.
- W2377886932 created "2016-06-24" @default.
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- W2377886932 date "2001-01-01" @default.
- W2377886932 modified "2023-09-23" @default.
- W2377886932 title "The Effects of Leonurus Heterophyllus Sweet on Blood Rheology and Thrombosis in Rat with Myocardial Ischemia" @default.
- W2377886932 hasPublicationYear "2001" @default.
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