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- W2377887055 abstract "Objective To explore the association of baseline blood pressure level in 1992 and its change from 1992 to 2002 with serum oreatinine (Scr) in a cohort of 2740 subjects in Beijing. Methods A baseline investigation on the risk factors of cardiovascular disease was carried out in a natural population of Beijing in 1992. The follow-up survey was conducted in 2002, adding Scr as a new index. Complete data were available for 2740 subjects. Elevation of Scr level was defined as Scr level from 115μmol/L to 133μmol/L in male and from 107μmol/L to 124μmol/L in female. Renal damage was defined as Scr133μmol/L in male and Scr124μmol/L in female. These two stages were identified as abnormity of Scr in this study. Results (1) In 2002, the mean level of scr was (87.52±20.33)μmol/L in the samples of 45-74 years old. Male [(96.36±15.92)μmol/L] had a significantly higher level than female [(80.44±21.22)μmol/L]. (2) In this population, the incidence of abnormal Scr was 8.7%. The incidence of male (13.6%) was significantly higher than that of female (4.4%). (3)The incidence of abnormal Scr continually increased with elevation of baseline blood pressure level (P0.01). After adjusting for gender, age, BMI and other factors,the odds ratios (OR)of abnormal Scr was 3.89 for BP≥180/110 mm Hg, compared to the group of BP 120/80 mm Hg. (4) The incidence of abnormal Scr was 6.6% in subjects who had normal BP in both 1992 and 2002, whereas the incidence was 12.4% in the subjects who were hypertensive in 1992 but controlled in 2002 and 16.9% in those who were hypertensive both in 1992 and 2002. Conclusion Effective control on hypertension will be helpful to prevent or postpone the elevation of Scr." @default.
- W2377887055 created "2016-06-24" @default.
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- W2377887055 date "2006-01-01" @default.
- W2377887055 modified "2023-09-23" @default.
- W2377887055 title "A cohort study on blood pressure and serum creatinine" @default.
- W2377887055 hasPublicationYear "2006" @default.
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