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- W2377889523 abstract "Objective To study the anti-influenza A virus(IAV,H1N1) effect of the serum containing volatile oil of Schizonepetae and Ramulus Cinnamomi in vitro. Methods The TC0 of the serum containing volatile oil of Schizonepetae and Ramulus Cinnamomi in MDCK cells was determined by CPE assay.The infectivity of IAV to MDCK cells was determined by hemagglutination test.The IAV inhibitory effect of the serum in vitro was determined by hemagglutination test and MTT colorimetric assay. Results The TC0 of the serum containing volatile oil of Schizonepetae and Ramulus Cinnamomi in MDCK cells both were 5%,which means the concentration of serum in reaction system should be less than 5%.The TCID50 of mouse-lung adapted strain of IAV A/PR/8/34(H1N1) to MDCK cells was 10-3.5/0.1ml.5%,3.5%,2.5% serum containing volatile oil of Schizonepetae and Ramulus Cinnamomi significantly inhibited the multiplication of IAV in MDCK cells,while the 5%,3.5% serum also showed the direct killing action to IAV. Conclusion The serum containing volatile oil of Schizonepetae and Ramulus Cinnamomi could significantly inhibit IAV multiplication in MDCK cells,while showed the direct killing action to IVA.The results were similar to the effect of valotile oil in vitro and in vivo,which confirmed the anti-influenza virus action of two drugs." @default.
- W2377889523 created "2016-06-24" @default.
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- W2377889523 date "2013-01-01" @default.
- W2377889523 modified "2023-09-23" @default.
- W2377889523 title "Study on the Antiviral Action of Serum Containing Volatile Oil of Schizonepetae and Ramulus Cinnamomi in Vitro" @default.
- W2377889523 hasPublicationYear "2013" @default.
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