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- W2377895345 abstract "Objective To investigate the value of matrix metalloproteinases-3(MMP-3) for the early diagnosis of acute coronary syndrome(ACS). Methods The levels of MMP-3 and creatine kinase isoenzyme(CK-MB) in peripheral blood at 4h after the onset of symptoms were detected in 87 cases with ACS(group A), which included 50 cases of acute myocardial infarction(group B) and 37 cases of unstable angina(group C).And another 43 healthy people were taken as normal controls(group D).Receiver operating characteristic(ROC) curves for MMP-3 and CK-MB in the diagnosis of ACS were established and analyzed. Results The levels of MMP-3 and CK-MB in groups of A and B were higher than those in group D(P0.05).The areas of MMP-3 under ROC curves in groups of A,B and C were 0.840(95%CI 0.371-0.903),0.675(95%CI 0.553-0.797) and 0.747(95%CI 0.665-0.829),respectively,which were all more than those of CK-MB [0.775(95%CI 0.675-0.875),0.378(95%CI 0.242-0.514) and 0.581(95%CI 0.486-0.677)]. Conclusion MMP-3 has higher sensitivity and specificity and can be taken as a supplementary marker for early diagnosis of ACS." @default.
- W2377895345 created "2016-06-24" @default.
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- W2377895345 date "2013-01-01" @default.
- W2377895345 modified "2023-09-27" @default.
- W2377895345 title "Value of matrix metalloproteinases-3 for early diagnosis of acute coronary syndrome" @default.
- W2377895345 hasPublicationYear "2013" @default.
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