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- W2377899043 abstract "Objective To investigate the therapeutic effect and antioxidative effect of pine needle extract(PNE) on rats with type 2 diabetes induced by high fat diet and STZ.Method Type 2 diabetic animal model was established by high-fat diet and low dose of STZ.After treatment with PNE(200,400,800 mg / kg) for 4 weeks,the serum fasting blood glucose(FBG),total cholesterol(TC),triglyceride(TG) levels,nitric oxide(NO) activities,superoxide dismutase(SOD) activities and malondialdehyd(MDA) levels were measured.Results Compared with those in diabetic group,FBG,TC and TG levels in diabetic rats treated with PNE were significantly decreased.PNE treatment significantly reduced NO activities and MDA levels,and elevated SOD activities in diabetic rats.Conclusion PNE can decrease blood glucose and blood lipids,has a therapeutic effect on rats with type 2 diabetes.The mechanism may be related to the antioxidant effect." @default.
- W2377899043 created "2016-06-24" @default.
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- W2377899043 date "2013-01-01" @default.
- W2377899043 modified "2023-09-24" @default.
- W2377899043 title "Antioxidative Effects of Pine Needle Extract on Rats with Type 2 Diabetes" @default.
- W2377899043 hasPublicationYear "2013" @default.
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