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- W2377925273 abstract "Objective To feed rats with high-salt diet of different concentrations,observe changes in artery systolic pressure of rat-tail,to investigate a reasonable period and concentration to lead to hypertention by purely feeding high-salt diet.Methods One hundred and thirty 3-week-old(weanling) male Wister rats were randomly divided into groups: Normal-diet-group(Group Ⅰ,n=10),4%-salt-diet-group(Group Ⅱ,n=30),6%-salt-diet-group(Group Ⅲ,n=30),8%-salt-diet-group(Group Ⅳ,n=30),feeding-8%-salt-diet-after-adult-group(Group Ⅴ,n=30).Artery systolic pressure of rat-tail and rats's weights were surveyed at different time.Results When rats were 25 weeks old,Group Ⅳ involved a higher rate of hypertension than GroupⅠ-Ⅲ,but there was no difference between 25 weeks old and 21 weeks old(P0.05).When rats were 21 weeks old,there was no difference between Group Ⅳ and Group Ⅴ(P0.05).Conclusion To adult Wistar rats,8%-salt-diet is a reasonable concentration and 12 weeks is a reasonable period to make hypertention models." @default.
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- W2377925273 date "2012-01-01" @default.
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- W2377925273 title "Experimental study of feeding different concentrations of high-salt-induced hypertension model" @default.
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