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- W2377963189 abstract "Objective To explore the different treatment options for hypertension with adrenal hyperplasia clinical perspective effect.Methods The patients with adrenal hyperplasia of hypertension were randomly divided into four groups:group A:nifedipine controlled release tablets 30mg+spironolactone 20mg(n= 30);group B:nifedipine controlled release tablets 30mg+spironolactone 40mg(n =31),group C:nifedipine controlled release tablets 30 mg+Irbesartan Tablets 150 mg+spironolactone 20 mg(n =29), group D:nifedipine controlled release tablets 30mg+Irbesartan Tablets 150mg+placebo(n=29),After discharge follow-up of 1,2,3,4weeks and 2,3,6,9and 12months of blood pressure and electrolyte. Assessed among groups before and after treatment of blood pressure,electrolyte levels.Results(1)12 months after treatment of 4set of systolic blood pressure decreased,respectively:13.4%,14.1%,18.0%, 16.9%;Diastolic blood pressure decreased,respectively:17.5%,17.8%,24.7%,22.9%.(2)1,2,6,9 and 12months of systolic blood pressure is lower than other groups,group C was statistically significant(3)1,9,12months of diastolic down from other groups,group C was statistically significant.(4)6,9 months in group B after treatment of potassium is higher than other groups,12months in group B,group C of potassium is higher than the other group,with statistical significance.(5)Group A significant effective,efficient,inefficient were 66.7%,26.7%,6.6%,group B was 80.6%,16.1%,3.3%,group C was 86.2%,10.3%,3.5%,group D was 82.8%,13.8%,3.4%.(6)four groups before and after treatment in patients with potassium and blood pressure were negatively correlated.(7)An gynecomastia appears in group B during treatment.Conclusion Four kinds of treatment programs can reduce blood pressure in patients with adrenal hyperplasia of hypertension,but nifedipine controlled release tablets 30mg+Irbesartan Tablets 150mg+spironolactone 20mg program is superior to other antihypertensive programs." @default.
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- W2377963189 date "2013-01-01" @default.
- W2377963189 modified "2023-09-23" @default.
- W2377963189 title "Different treatment options for hypertension with adrenal hyperplasia clinical perspective effect" @default.
- W2377963189 hasPublicationYear "2013" @default.
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