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- W2378015242 abstract "Objectives To investigate the relevance between the high sensitive C-reactive protein (hs-CRP) and insulin resistance index (IRI) and the severity of coronary artery disease (CAD). Methods 308 CAD patients diagnosed by coronary angiography(CAG) were divided into 3 groups: GroupⅠ(123 patients without diabetes mellitus and impaired glucose tolerance),Group Ⅱ(87 patients with impaired glucose tolerance) and Group Ⅲ(98 patients with diabetes mellitus). Free blood glucose (FBG),2h postprandial blood glucose(2hBG),blood lipids,fasting insulin (FINS),hs-CRP and hemoglobin Alc(HbA1C)were determined. IRI was calculated by HOMA model and the severity of coronary artery disease were reflected by the degree of coronary stenosis and numbers of diseased coronary arteries. 92 patients without CAD diagnosed by CAG were enrolled into control group (Group C),and all the CAD patients were divided into 2 groups (ACS group-96 patients and non-ACS group-212 patients). Results There were no obvious statistical difference in the level of hs-CRP among GroupⅠ,GroupⅡand Group Ⅲ,but the level of hs-CRP in aforesaid 3 groups was much higher than that of Group C,and hs-CRP of ACS group was higher than that of non-ACS group and Group C. There was obvious positive correlation between hs-CRP and HbA1C,FINS and IRI,but there was no obvious correlation between hs-CRP and FBG,2hBG and blood lipids. There were obvious correlation between HbA1C,FINS,IRI,blood lipids and the severity of CAD,but there was no between hs-CRP and the severity of CAD. Conclusions It has no obvious effect on the level of hs-CRP in spite of with or without DM in CAD patients. hs-CRP is the better index to forecast the acute heart events. There is apparent correlation between hs-CRP and HbA1C,FINS,IRI,but there is no between hs-CRP and FBG,2hBG,blood lipids. There is obvious correlation between the severity of CAD and HbA1C,FINS,IRI,blood lipids,but there is no between it and hs-CRP." @default.
- W2378015242 created "2016-06-24" @default.
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- W2378015242 date "2007-01-01" @default.
- W2378015242 modified "2023-09-22" @default.
- W2378015242 title "The clinical relevance between high sensitive C-reactive protein and insulin resistance index and severity of coronary artery disease" @default.
- W2378015242 hasPublicationYear "2007" @default.
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