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- W2378028826 abstract "Objective: To explore the association between serum alanine aminotransferase(ALT) and acute ST-segment elevation myocardial infarction(STEMI), and also to investigate whether ALT is the new risk predictor for acute STEMI. Methods: A total of 909 patients were included in the analysis. Coronary angiography was the gold standard for diagnosis of coronary heart disease. The complement inhibition treated with angiography evaluated 554 patients with STEMI and 355 patients without coronary heart disease(control group). There were two different subgroups divided inpatients with STEMI(1)According to the degree of coronary lesions,there were 154,176 and 224 cases with single-branch group,double-branch group and multi-branch group respectively;(2)According to the time from AMI to fasting blood,three subgroups were divided(0-24 h:296 cases,24-48 h:124 cases,and more than 48 h :134 cases).The basic clinical data, biochemical data and coronary angiography were prospectively collected from the Department of Cardiology, especially STEMI from cardiac ICU. Results: Compared with control group, there were statistically significance in age, blood urea nitrogen, creatinine, aspartate aminotransferase(AST), ALT, high density lipoprotein(P0.01); In subgroups analysis closely association with the degree of coronary stenosis(P0.05) and with the time from AMI to fasting blood was tested in patients with STEMI(P0.01).The risk predictors of STEMI were age(OR= 1.068), AST(OR=1.270),Cr(OR=1.041) and ALT(OR=0.911) from logistic regression analysis. Conclusion: ALT is closely associated with acute STEMI, ALT is not only new risk predictor for acute STEMI but also a positive diagnostic value for acute myocardial infarction." @default.
- W2378028826 created "2016-06-24" @default.
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- W2378028826 date "2014-01-01" @default.
- W2378028826 modified "2023-09-28" @default.
- W2378028826 title "Clinical study of serum alanine aminotransferase in patients with acute ST-segment elevation myocardial infarction" @default.
- W2378028826 hasPublicationYear "2014" @default.
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