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- W2378054920 abstract "Objective To investigate the relataionship between the expressions of CDX2 and CA242 protein and their clinicopatholoic in colorectal cancer in elderly patients.Methods Immunohistochemical staining was used to detect the expressions of CDX2 and CA242 protein in 90 cases of colorectal carcinoma and 30 cases of normal colorectal mucosa.Results The expressions of CDX2 and CA242 of the carcinoma were 65.6%(59/90) and 75.6%(68/90),respectively.CDX2 protein was lower than that in normal colorectal mucosa(93.3%,P0.05),but the CA242 protein in carcinoma was higher than that in mormal colorectal mucosa(10.0%,P0.05).The expressions of CDX2 protein and CA242 protein were positively correlated with tumor grading,Duke's staging,serosa infiltration and lymph node metastasis of colorectal cancer(r=-0.30,P0.05).Negative correlation was found between CDX2 and CA242 protein(P0.05).Conclusion The study shows that a correlation exists between the CDX2 protein and CA242 protein expressions and the potential of invasion and metastasis in colorectal cancer.CDX2 and CA242 protein may be prognostic indicators in colorectal cancer in elderly patients." @default.
- W2378054920 created "2016-06-24" @default.
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- W2378054920 date "2012-01-01" @default.
- W2378054920 modified "2023-09-23" @default.
- W2378054920 title "Relationship between Expressions of CDX2 and CA242 Protein in Colorectal Cancer and its Clinicopathological Features in Elderly Patients" @default.
- W2378054920 hasPublicationYear "2012" @default.
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