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- W2378066312 abstract "Objective:To detect the expressions of CC chemokine receptor 7(CCR7) and blood vessels endothelial growth factor-C(VEGF-C) in laryngeal squamous cell carcinoma(LSCC) and to explore the interrelationship and their relation with lymph node metastasis of LSCC.Methods:40 samples of LSCC tissues were selected as the experimental group.The expression of CCR7 and VEGF-C in all the tissues were detected by immunohistochemistry and combined with clinical medical data to be statistically analyzed.Results:CCR7 and VEGF-C protein in laryngeal carcinoma showed strong positive expression,and the expression of CCR7 and VEGF-C was significantly higher than that in the control group(P0.05).Also the positive rate in the lymph node metastasis and expression intensity were higher than those without lymph node metastasis,the difference was significant(P0.05).Conclusion:The expression of CCR7 and VEGF-C is closely related to laryngeal cancer lymph node metastasis in laryngeal cancer,the joint detection of the two factors in endoscopic biopsy tissues can help to predict the occurrence of early lymph node metastasis in laryngeal cancer." @default.
- W2378066312 created "2016-06-24" @default.
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- W2378066312 date "2011-01-01" @default.
- W2378066312 modified "2023-09-28" @default.
- W2378066312 title "Correlation of CCR7 and VEGF-C expression with lymphatic metastasis in laryngeal carcinoma" @default.
- W2378066312 hasPublicationYear "2011" @default.
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