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- W2378174120 abstract "Objective To discuss the effects of large dosage of piperazine ferulate on pulmonary arterial blood pressure,blood gas and hemorheology in treating exacerbations of pulmonary heart disease.Methods Forty patients with exacerbations of pulmonary heart disease were randomly assigned as treatment group(large dosage of Piperazine Ferulate tablets plus routine therapy) and control group(routine therapy).Each group had 20 cases and received 14 days' treatment.Average pulmonary artery blood pressure(mPAP),partial pressure of oxygen(PaO2),partial pressure of carbon dioxide(PaCO2),arterial oxygen saturation(SaO2),blood viscosity,plasma viscosity,blood reduced viscosity and hematocrit were detected.Results Both the mPAP and PaCO2 of the treatment group and control group were decreased after treatment,both the PaO2 and SaO2 of the treatment group and control group were increased,the differences were statistically significant(t = 3.17,3.34,2.86,3.28,2.93,2.32,2.37,2.68,P 0.05).After treatment,the differences of mPAP,PaCO2,PaO2 and SaO2 were statistically significant between the two groups(t = 2.14,2.78,2.78,3.08,P 0.05).The blood viscosity,plasma viscosity,blood reduced viscosity and hematocrit of two groups dropped after treatment,the differences were statistically significant(t = 3.26,3.03,2.88,2.72,2.78,2.46,2.36,2.67,P0.05).After treatment,the differences of the blood viscosity,plasma viscosity,blood reduced viscosity and hematocrit were statistically significant between the two groups(t =2.24,2.65,2.82,2.37,P0.05).Conclusions Routine therapy uniting with large oral dosage of piperazine ferulate tablets may obviously improve the pulmonary arterial blood pressure,pulmonary ventilation and pulmonary gas exchange in patients with pulmonary heart disease,as well as the hemorheology under hypercoagulability status." @default.
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- W2378174120 date "2010-01-01" @default.
- W2378174120 modified "2023-09-23" @default.
- W2378174120 title "Effects of piperazine ferulate on pulmonary arterial blood pressure,blood gas and hemorheology in treating exacerbations of pulmonary heart disease" @default.
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