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- W2378251036 abstract "[Objective]To determine the relationship of the Gly972Arg polymorphism of insulin receptor substrate 1(IRS-1)gene with type 2 diabetes mellitus in Chinese Han population in Hainan.[Methods]Gly972Arg mutation of IRS-1 gene in 60 patients with type 2 diabetes and 60 control subjects was analyzed by polymerase chain reaction-restriction fragment length polymorphism technique,followed by polyacrylamide gel electrophoresis and silver staining.[Results]The frequency of Gly972Arg mutation of IRS-1 gene w as significantly higher in patients with type 2 DM than that in control subjects(13.3% vs 3.3%,χ2 = 7.2,P﹤0.01).[Conclusion]Gly972Arg mutation of IRS-1 gene may play an important role in Chinese Han population in Hainan." @default.
- W2378251036 created "2016-06-24" @default.
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- W2378251036 date "2011-01-01" @default.
- W2378251036 modified "2023-09-28" @default.
- W2378251036 title "RELATIONSHIP BETWEEN THE GLY972ARG POLYMORPHISM OF INSULIN RECEPTOR SUBSTRATE 1 GENE AND TYPE 2 DIABETES MELLITUS IN THE CHINESE HAN POPULATION IN HAINAN" @default.
- W2378251036 hasPublicationYear "2011" @default.
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