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- W2378269991 abstract "Objective:To assess the feasibility of presurgical fMRI for the location and lateralization of language function in patients with low grade glioma.Methods:Fifeen patients with low grade gliomas confirmed by pathology involving left frontal and temporal lobe performed preoperative fMRI studies with picture naming tasks.Ten healthy volunteers were enrolled as control subjects.The related workstation was used to postprocess fMRI data.The activated language related areas were recorded and activated volume was calculated,the lateral index(LI) was calculated to evaluate the asymmetry of hemisphere.Results:The activation areas including bilateral inferior frontal gyrus and middle frontal gyrus(left dominant),left superior temporal gyrus,bilateral superior parietal lobule(left dominant) and premotor area in control subjects.Bilateral inferior frontal gyrus,bilateral middle frontal gyrus,bilateral superior temporal gyrus(left dominant) and bilateral parietal lobule were the most common activation areas in patients.In addition,bilateral occipital lobes and cerebellum were common seen in both groups.Eight with left hemisphere dominant and two with bilateral hemisphere dominant and the LI was 84.61% in control subjects.However,five patients showed left hemisphere dominant and ten with right or bilateral hemisphere dominant and the lateral index was 60.15% in patients.Conclusion:fMRI is a reliable technique in identifying the location and lateralization of language in patients with low grade glioma and helpful in making preoperative planning." @default.
- W2378269991 created "2016-06-24" @default.
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- W2378269991 date "2009-01-01" @default.
- W2378269991 modified "2023-09-26" @default.
- W2378269991 title "Preoperative fMRI for identifying language cortices in patients with low grade gliomas" @default.
- W2378269991 hasPublicationYear "2009" @default.
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