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- W2378293322 abstract "Objective To investigate the inherent cholinergic system in immunocytes and immune organs of rats. Methods Immunofluorescence, flow cytometry and immunohistochemical method were used to detect the expression of nicotinic acetylcholine receptors α7 (nAChRα7), choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) in peripheral blood CD4+T lymphocytes, peritoneal macrophages, synovial cells and celiac lymph nodes of rats. Results The presence of nAChRα7, ChAT and AChE in immunocytes and immune organs was detected. Macrophage of lymph node, peritoneal macrophages and synovial macrophage were abundant in expression of nAChRα7, ChAT and AChE. The lymphocytes of celiac lymph nodes were weak in expression and only less part of CD4+T lymphocytes in peripheral blood expressed nAChRα7 and ChAT(15.88%±0.753% and 23.09%±0.671%, respectively). Conclusion The inherent cholinergic system is widespread in immunocytes and immune organs. Macrophages and lymophacytes play different roles in the inherent cholinergic system." @default.
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- W2378293322 date "2005-01-01" @default.
- W2378293322 modified "2023-09-23" @default.
- W2378293322 title "Inherent cholinergic system in immunocytes and immune organs of rats" @default.
- W2378293322 hasPublicationYear "2005" @default.
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