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- W2378302298 abstract "Objective To investigate the effect of space saturation technique on the quality of proton magnetic resonance spectroscopy(1H-MRS) for amygdala.Methods 22 healthy volunteers were enrolled and scanned at a 3.0T MR scanner.Single voxel 1H-MRS of amygdala with and without space saturation bands around the region of interest was performed using point-resolved spectroscopy series(PRESS,TR/TE=1500/30 ms).Raw spectral data were processed and signal-to-noise ratio of creatine(Cr-SNR),water-suppression level,full width at half maximum(FWHM) and root mean square(RMS) noise were obtained and compared between groups with and without saturation bands.Results The Cr-SNR of spectra without and with saturation bands was 15.506±6.623 and 22.935±7.270,respectively(increased by(47.9%±24.94%),P0.001).The water-suppression level of spectra without and with saturation bands was(93.888%±1.079%) and(95.722%±0.461%),respectively(increased by(1.95%±0.68%),P0.001).The FWHM of spectra without and with saturation bands was 7.00±1.113 and 6.82±1.181,respectively(decreased by(2.57%±1.12%),P0.05).The RMS noise of spectra without and with saturation bands was 0.606±0.0615 and 0.589±0.0470,respectively(reduced by(2.81%±1.68%),P0.05).ConclusionApplication of space saturation technique significantly elevates the Cr-SNR and the water-suppression level,and thus improves the spectral quality of amygdala without additional scanning time." @default.
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- W2378302298 date "2011-03-01" @default.
- W2378302298 modified "2023-09-28" @default.
- W2378302298 title "[MR spectroscopy of amygdala: space saturation technique improves spectral quality]." @default.
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