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- W2378360003 abstract "Objective:To observe the amount of collagen type Ⅲ and(amino-teminal propeptide of procollagen Ⅲ) PⅢNP in cardinal ligament and vaginal wall of patients with pelvic organ prolapse,explore the relationship between metabolism of collagen type Ⅲ and onset of pelvic organ prolapse.Methods:The levels of collagen type Ⅲ from cardinal ligament and vaginal wall of 13 patients with pelvic organ prolapse and 13 patient with uterine benign lesions were detected by immunohistochemical staining,the level of PⅢNP was detected by enzyme-linked immunosorbent assay.Results:The level of collagen type Ⅲ from patients with pelvic organ prolapse was lower than that from patient with uterine benign lesions,while the level of PⅢNP reversed(P0.05).Conclusion:The decrease of collagen type Ⅲ in cardinal ligament and vaginal wall maybe caused by the increase of collogen degradation,which effects the intensity and flexibility of pelvic floor tissues,pelvic organ prolapse occurs." @default.
- W2378360003 created "2016-06-24" @default.
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- W2378360003 date "2009-01-01" @default.
- W2378360003 modified "2023-10-05" @default.
- W2378360003 title "Changes of metabolism of collagen type III in cardinal ligament and vaginal wall of patients with pelvic organ prolapse" @default.
- W2378360003 hasPublicationYear "2009" @default.
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