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- W2378361252 abstract "Objective To study the characteristics of a novel human testis-specific gene, HSD-9, and its encoding protein. Methods HSD-9 was a novel gene from a human germ cells-specific ESTs library established in our laboratory. We used an electronic cloning method to obtain HSD-9 gene, and analyzed the characteristics of this novel gene and encoding product by bioinformatics methods, detected its expressing profile using a Northern blot assay, prepared specific rabbit polyclonal antibodies against HSD-9 protein, observed the localization of this protein in the germ cells and some somatic cells with confocal microscopy. Results HSD-9 was expressed in human testes, and its rat homolog was found in the varying germ cells. HSD-9 protein could partly be colocalized with clathrin. Conclusions HSD-9 is specific in human testes, and the expression pattern of its encoding product is similar to those of some endocytosis proteins. It is speculated that HSD-9 protein may function in the endocytosis." @default.
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- W2378361252 date "2007-06-01" @default.
- W2378361252 modified "2023-09-26" @default.
- W2378361252 title "Characteristics of a Novel Human Testis-specific Gene,HSD-9,and Its Encoding Protein" @default.
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