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- W2378402838 abstract "Objective To investigate the efficacy of Atorvastatin and Clopidogrel for the patients with unstable angina,and to explore the impact on IL-6,hs-CRP and prognosis.Methods All 68 patients were divided into observation group(conventional therapy and Atorvastatin and Clopidogrel) 36 cases and the control group 32 patients(conventional treatment),and after treatment,the improvement degree of angina symptoms and ECG and IL-6,hs-CRP changes and the incidence rates of cardiovascular events were compared.Results The overall efficiency of angina symptoms which improved(91.67%) was significantly higher than the control group(78.13%).And the duration of the observation group was significantly shorter than the control group(P 0.05).ECG response rate of the observation group(94.44%) was significantly higher than the control group(81.25%)(P 0.05).After treatment,the level of TC,TG,IL-6,hs-CRP of the observation group was significantly lower than the control group(all P 0.05).The total cardiovascular events incidence rate of the observation group(5.56%) was significantly lower than the control group(21.88%)(P 0.01).Conclusion Atorvastatin combined Clopidogrel in unstable angina has good efficacy and low cardiovascular events incidence,and may be considered by blocking the generation of hs-CRP,lower serum hs-CRP,IL-6 levels and inhibit pro-inflammatory effects,thereby reducing the incidence of myocardial infarction." @default.
- W2378402838 created "2016-06-24" @default.
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- W2378402838 date "2012-01-01" @default.
- W2378402838 modified "2023-09-23" @default.
- W2378402838 title "Impact of Atorvastatin and Clopidogrel treatment in patients with unstable angina on IL-6 and hs-CRP and prognosis" @default.
- W2378402838 hasPublicationYear "2012" @default.
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